• Non-stimulating bulk softeners such as docusate (solace) help to soften the stool and mineral oil or olive oil can
be used to loosen the stool.
• Glycerin suppositories or Dulcolax suppositories may be used to stimulate bowel action as a contact laxative.
(Dulcolax may cause cramping.)
• Bowel stimulants such as Reglan may be useful.
• Lactulose (chronulac) is an acidifier that softens the stool and increases the number of bowel movements.
All laxatives should be used with care. If you use them continually, you might develop a gastrointestinal irritation that can make it difficult to regain your normal bowel habits once you stop taking them. Increasing doses can also make your colon and rectum insensitive to the normal reflexes that stimulate a bowel movement.
Hints to Prevent and Relieve Constipation
• Eat foods that are high in fiber and bulk. These include fresh fruits and vegetables (raw or cooked with skins
and peels on), dried fruit, whole-grain breads and cereals and bran. Avoid raw fruits and vegetables, including
lettuce, when your white blood cell count is lower than 1,800.
Note: You should start a high-fiber diet before taking a chemotherapy drug that causes constipation.
• Drink plenty of fluids—8 to 10 glasses a day. Avoid dehydration. Try to drink highly nutritional fluids
(milkshakes, eggnogs and juices) rather than water, since liquids can be filling and may decrease your appetite.
